Protein Details: Gap junction beta-6 protein

Protein ID

ICDB_Pro_0297

Protein Name

Gap junction beta-6 protein

Gene Name

GJB6

Organism

Homo sapiens (Human)

Length

261 amino acids

AlphaFoldDB

AF-O95452-F1-model_v4.pdb

Function

Sequence

MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCKNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIEDIKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSKRAQTQKNHPNHALKESKQNEMNELISDSGQNAITGFPS

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Clouston Syndrome and Deafness;Autosomal Dominant 3B

Location

DOI ID

10.1038/12612; 10.1006/geno.1999.6002; 10.1038/ng1285; 10.1093/dnares/12.2.117; 10.1038/nature02379; 10.1101/gr.2596504; 10.1016/j.gene.2004.12.048; 10.1056/nejmoa012052; 10.1136/jmg.2004.028324; 10.1038/79851; 10.1046/j.0022-202x.2001.01689.x; 10.1111/j.1365-2133.2009.09137.x

RefSeq

NP_001103689.1; NP_001103690.1; NP_001103691.1; NP_006774.2; XP_016875846.1; XP_016875847.1; XP_016875848.1; XP_016875849.1